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Pulmonary embolism (PE) is the leading cause of in-hospital death and the third most frequent trigger of cardiovascular death. The clinical presentation of PE is variable, and selecting the suitable remedy for individual patients will be challenging. Traditionally, therapy of PE has concerned a choice of anticoagulation, thrombolysis or surgery; nonetheless, a spread of percutaneous interventional applied sciences have been developed which can be underneath investigation in patients with intermediate-excessive-risk or high-danger PE. These interventional technologies include catheter-directed thrombolysis (with or without ultrasound assistance), aspiration thrombectomy and combos of the aforementioned ideas. These interventional remedy choices may result in a extra rapid improvement in right ventricular operate and pulmonary and/or systemic haemodynamics specifically patients.